Polynucleotide-Chitosan Complex, an Insoluble but Reactive Form of Polynucleotide.

Induced Polynucleotide Kinase, Polynucleotide Ligase, and Deoxyribonucleic Acid Polymeraset

The mechanism of action of T4-induced polynu-cleotide kinase on short single-stranded deoxyoligonucleotideshas been investigated.It was found that the phosphorylationreaction catalyzed by T, polynucleotide kinase could be re-versed. Thus, a 5 ’-3*P-labeleddeoxyoligonucleotide and ADPon incubation with the enzyme formed [Y-~~PJATP.In addi-tion some radioac...

Enzymes of Polynucleotide Metabolism

The latest memoir of the Society for Endocrinology presents the papers and discussions of a 1958 symposium on selected aspects of comparative and human sex morphology. It is gratifying that discussions of bacteria and invertebrate forms are included. Several authors examine the important question of genetic and hormonal controls of sex differentiation. The possibility of regulating the sex rati...

The fuzzy polynucleotide space revisited

OBJECTIVE A theory of fuzzy polynucleotides, including an n-dimensional metric fuzzy polynucleotide space, has been previously introduced by the present author for fuzzy-theoretical analysis of nucleic acids [Sadegh-Zadeh K. Fuzzy genomes. Artif Intell Med 2000;18:1-28; Sadegh-Zadeh K. Ein Verfahren zur Fuzzydecodierung und Fuzzydechiffrierung von Informationen. Offenlegungsschrift DE 199 36 92...

Nanoparticulate systems for polynucleotide delivery

Nanotechnology has tremendously influenced gene therapy research in recent years. Nanometer-size systems have been extensively investigated for delivering genes at both local and systemic levels. These systems offer several advantages in terms of tissue penetrability, cellular uptake, systemic circulation, and cell targeting as compared to larger systems. They can protect the polynucleotide fro...

Polynucleotide evolution and branching processes.